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KMID : 0854720090290010027
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Korean Journal of Asthma, Allergy and Clinical Immunology
2009 Volume.29 No. 1 p.27 ~ p.32
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Clinical Outcomes after Recovery from Severe Asthma Exacerbation -the Second Report-
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Chung Hye-Young
Choi In-Seon
Lee Woo-Jin
Ban Hee-Jeong
Lee Seong-Ji
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Abstract
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Background: Approximately 10% of patients with nearfatal asthma (NFA) die within a year of an attack, and close follow-up is helpful to prevent fatal events.
Objective: To investigate the clinical outcomes of acute severe asthma and whether close follow-up may help to improve clinical outcomes.
Method: Asthma patients (N=225), who were hospitalized due to severe exacerbation during the period 1998∼2006, were followed up using questionnaires or phone interviews. The 146 patients, who had regularly visited our hospital until the examination, were assigned as regular hospital visitor.
Result: Twenty-two (9.8%) of the total patients and 7 (15.9%) of 44 NFA patients died (mean follow-up period: 138.9 weeks). The mortality rate was significantly lower in regular hospital visitors than in the others (total: 6.2% vs. 16.5%, P＜0.05; NFA: 3.4% vs. 40.0%, P＜0.01). The regular hospital visitors controlled their asthma better (controlled/partly controlled/uncontrolled: 75/38/33 vs. 20/ 28/31; P＜0.001), had better knowledge of asthma (9.7± 0.2 vs. 8.5±0.3, P＜0.01) and used inhaled steroid more frequently (74.7% vs. 55.7%, P＜0.001) than the others.
Conclusion: Not a few patients with acute severe asthma die after discharge from hospital. However, close follow-up and adequate asthma control seem to help in the reduction of asthma mortality.
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KEYWORD
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Asthma, Exacerbation, Mortality, Outcome
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